Intra-articular injections of PRP resulted in no serious adverse effects and significantly reduced pain in patients with ankle osteoarthritis (OA), according a new study published last week in the journal, Foot & Ankle International.
20 patients (a total of 20 ankles) with ankle OA received injections of PRP directly into the ankle joint under ultrasound guidance, every 2 weeks for 3 treatments. Adverse events and efficacy were assessed at 4, 12, and 24 weeks after the last injection.
No serious adverse effects were observed during the follow-up period. Overall, the amount of pain reduction was maximal at 12 weeks after the last injection, and the effect was reduced at 24 weeks. The patients with more severe OA had worse scores in all outcomes than those with milder OA.
Conclusion: PRP treatment can be safe and effective and may be an option in the treatment of ankle OA.
Commentary by Dr. Tortland: Studies investigating the benefits of PRP on OA have largely focused on the knee and hip. Although we know anecdotally that PRP can work just as well in other arthritic joints, this study lends scientific support to the positive results that we’ve been seeing clinically in the office when treating ankle OA.